Diuretic-induced hypokalemia

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Hypokalemia, glucose intolerance, and hyperinsulinemia during diuretic therapy.

Hypokalemia and glucose intolerance may result from diuretic therapy. Increases in plasma insulin and glucose levels have been observed in thiazide-treated hypertensive patients and have been attributed to a diminished insulin sensitivity induced by diuretic therapy. To investigate the effects of hypokalemia on glucose tolerance and insulin secretion, we studied 21 essential and nine diabetic h...

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Diuretic-induced hypokalemia in uncomplicated systemic hypertension: effect of plasma potassium correction on cardiac arrhythmias.

Sixteen patients with diuretic-induced hypokalemia underwent 24-hour ambulatory electrocardiographic monitoring during and after correction of hypokalemia. Plasma potassium averaged 2.83 +/- 0.08 mEq/liter before and 3.73 +/- 0.06 mEq/liter after correction with potassium chloride, triamterene or both. Premature atrial contractions decreased in 6 patients, increased in 6 and remained unchanged ...

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Hypokalemia and ST Elevation Induced by Angiotensin II Type 1 Receptor Blocker and Thiazide Diuretic Combination

The combination of an angiotensin II type 1 receptor blocker (valsartan) and a thiazide diuretic (hydrochlorothiazide) has been evaluated in the treatment of patients with hypertension in several clinical trials. The valsartan/hydrochlorothiazide (VAL-HCT) combination was found to be generally more effective than either drug given alone. The incidence of adverse events in VAL-HCT recipients was...

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ژورنال

عنوان ژورنال: Kidney International

سال: 1985

ISSN: 0085-2538

DOI: 10.1038/ki.1985.229